Recent Studies Show Benefits of Adenosine Triphosphate (ATP) Supplementation.

ATP is a substance present in all living cells that provides energy for many metabolic processes. As we age, intracellular levels of ATP drop significantly.

Several published pre-clinical and human clinical trials have shown that extracellular ATP and its major degradation product, adenosine, activate specific ATP and adenosine receptors on the cells that line the blood vessel walls. This improves blood vessel tone and the widening of blood vessels resulting from relaxation of smooth muscle cells within the vessel walls thus increasing the flow of blood to the heart, brain and peripheral areas, especially to skeletal muscles. This also increases the delivery of glucose, nutrients and oxygen to working and recovering muscles and the removal of catabolic waste products. The end result of these actions is increased energy and vitality as well as improved athletic performance and recovery.

Dr. Eliezer Rapaport, one of the foremost world authorities on ATP, has been studying ATP and its effects for decades. As a result, Dr. Rapaport has been issued several unique ATP patents. TSI Health Sciences of Missoula, Montana has acquired exclusive license to several of Dr. Rapaport's patents and have produced the first ATP formulation that is effective in an orally delivered form. This product is called PEAK ATP®.

A randomized, double-blind, placebocontrolled trial, performed at the Cooper Institute Centers for Integrated Health Research, studied the effects of PEAK ATP® on 27 healthy male athletes aged 18-45. Men who took a high dose (225 mg) of the supplement daily for two weeks were able to do 18.5% more reps than before they started the treatment and total lifting volume increased by 1,552 pounds-a 28.2% gain. 1

ATP is also being studied in patients with advanced solid tumors to see if it can decrease weight loss and improve muscle strength. Preliminary data suggests that ATP may actually help terminal cancer patients "get bigger and stronger." The investigators observed that ATP seems to favorably impact lung cancer patients who have failed chemo-and/or radiation therapy by allowing them to regain their appetite and to maintain their body composition. 2

PEAK ATP® has been shown safe and non-toxic. PEAK ATP® is not a stimulant however, it does boost energy without effecting heart rate or blood pressure. PEAK ATP® increases cellular energy and blood flow, benefiting overall health as well as circulatory and mental health.


1. Jordan AN et al. “Effects of oral ATP supplementation on anaerobic power and muscular strength.” Med Sci Sports Exerc. 36, 6:983-90, 2004.

2. Beneficial effects of adenosine triphosphate on nutritional status in advanced lung cancer patients: a randomized clinical trial. J Clin Oncol. 2002;Jan 15;20(2):371-378.

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease. The information on this Web site or in emails is designed for educational purposes only. It is not intended to be a substitute for informed medical advice or care. You should not use this information to diagnose or treat any health problems or illnesses without consulting your health practitioner.

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New Study Confirms Importance of Vitamin E

A three-year study of micronutrients in older adults in Italy indicates a linkage between higher blood levels of vitamin E and better performance in standardized physical tests. Results of the study were published in the January 23, 2008 issue of the Journal of the American Medical Association.

The study was conducted with 698 adults with an average initial age of 73.7 years, in two towns in the Tuscany province of Italy, near Florence. Blood samples were analyzed at the start of the study and after a three-year interval for the micronutrients vitamin B6, vitamin B12, vitamin D, vitamin E, folic acid and iron. Participants were also given a standardized physical performance test, the Short Physical Performance Battery (SPPB).

Participants in the study were interviewed by the research team of nutritionists and geriatric physicians from the U.S. and Italy to determine their diets and estimate their micronutrient intake. No dietary supplements were given to participants of the study.

After three years, participants were re-tested for micronutrients and physical performance. Only two factors were linked statistically with lower scores on the SPPB—age and lower serum concentration of vitamin E.

The SPPB includes three tests—the best of two attempts at walking four meters distance, five repeated chair rises with hands folded across the chest, and standing balance attempts in progressively challenging positions. The SPPB score is considered a reliable and sensitive indicator of clinically important physical changes in adults.

The research team, led by nutritionists and physicians from Cornell and Yale University, concluded that clinical trials may be useful to determine if there is a baseline serum vitamin E concentration for reducing functional decline in older adults.

Because the study did not involve vitamin supplements, there are no recommendations for increasing vitamin E intake in the report. The results may encourage adults to ensure their diets include enough whole grains, nuts, leafy green vegetables or supplements to sustain their vitamin E levels.
Copyright 2008 Ron Cotnam

Ron Cotnam is the proprietor of:
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Improve Your Health with Antioxidant Supplements

Antioxidants are among the most important substances that should be present in your body at all times. These substances are essential in helping your body fight harmful free radicals. Many different kinds of foods are rich in antioxidants but you can also get your daily supply from antioxidant supplements.

An adequate amount of antioxidants in the body will keep you well-protected against cell damage and infection, which is mostly caused by the free radicals released by your own body. Most people do have sufficient levels of antioxidants. However, those who suffer from certain vitamin deficiencies may not have enough antioxidants in their body to protect themselves from the damaging effects of free radicals. This is why antioxidant supplements can significantly help in keeping the body healthy overall.

Most antioxidant supplements come in the form of herbal or organic tablets. These supplements are great for the prevention of several different kinds of illnesses, restoring the body's energy levels, preventing the unnecessary clotting of blood and even improving sex drive. Eating a balanced diet and getting adequate amounts of rest can further enhance the effects of antioxidant supplements.

Natural antioxidant supplements are considered to be the better option than synthetic antioxidant supplements due to several reasons. For one, the body absorbs natural antioxidant supplements much more easily and efficiently. Synthetic antioxidants can be quite effective as well, but because of their chemical composition, the body can take a longer time to absorb these substances. Furthermore, these artificial antioxidant supplements may trigger some undesirable side effects, which do not occur with the consumption of natural antioxidant supplements.

Many people make the mistake of assuming that just because they are regularly taking antioxidant supplements, they are free to eat any kind of food they want. This is not true at all. Antioxidant supplements are only meant to enhance, not replace, the natural nutrients you can get from the regular foods in your daily diet.

In supplementation, as in diet, it is important to acquire antioxidants from a variety of sources. There are several reactive oxygen molecules produced in cells . These include hydrogen peroxide, hypochlorous acid, and free radicals such as hydroxyl radical and the superoxide anion. There are two divisions of antioxidants, those soluble in water (Vitamin C, Lipoic acid, etc.) and those soluble in lipids (Vitamin E, Carotenes, Coenzyme Q, etc.). Water soluble antioxidants interact with oxidants in the cell cytosol (intracellular fluid) and blood plasma. Lipid soluble antioxidants protect cell membranes from damage caused by lipid peroxidation. With the interdependent and synergistic effects various metabolites and enzyme systems have on one another, the effectiveness of one antioxidant may depend on the function of other antioxidants in the system. The effectiveness of any one antioxidant not only depends on its concentration but, also on its reactivity towards the particular type of reactive oxygen molecule being considered.

Besides taking antioxidant supplements, eating foods that are rich in antioxidants can help reduce your body's susceptibility to illnesses and infections. These foods include leafy green vegetables, most fruits and whole grain products. For example, Vitamin C and Caroteniods are found in fruits and vegetables. Vitamin E (tocopherols, tocotrienols) can be obtained from vegetable oils. And polyphenolic antioxidants can be found in tea, soy, grapes, berries, olive oil, cinnamon, oregano and red wine. If you eat adequate quantities of these foods on a daily basis, you can be sure your body will have the necessary antioxidants to fight the free radicals and other harmful chemicals that might find their way into your system. However, if you think your regular diet does not provide you with sufficient amounts of antioxidants, consider taking some antioxidant supplements to boost your body's defenses.
Copyright 2008 Ron Cotnam
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Ron Cotnam is the proprietor of August Moon Nutrition

These statements have not been evaluated by the FDA.

The content on this page is provided for informational purposes and is not intended as medical advice.